There is this Flash animation that tells the story of a woman who believes God talks to her through Scrabble, which entirely reminds me of a particular scene from The Hitchhiker's Guide to the Galaxy trilog—or should I say pentology. In that scene, the protagonist of the book, Arthur Dent, who is one of the last living inhabitants of Earth AKA the largest computer in the Universe which was computing the question to the answer of life, the universe, and everything. As is well known, the answer is 42. Unfortunately, the Earth is destroyed right before it figures out the answer, so Arthur decides to see if somehow the answer if encoded in his brain, and he starts blindly picking out Scrabble tiles from a bag. The question that he comes up with is "WHAT DO YOU GET WHEN YOU MULTIPLY SIX BY NINE," leading him to comment that he's always thought that there was something intrinsically wrong with the universe.